Mathematical Biology Seminar

 Fall 2012
Organizer:
Isabel Darcy

September| October| November| December

Spring 2012| Fall 2011| Spring 2011| Fall 2010| Spring 2010|

The Mathematical Biology Seminar is held every Monday between 3:30-4:20 PM in 110 MLH.


August
August 27, 2012
3:30 PM
Speaker Isabel Darcy
Title Condensin-bound DNA
Room 110 MLH
 
September
September 3, 2012 (Labor Day)
3:30 PM
Speaker -
Title -
Room -
 
September 10, 2012
3:30 PM
Speaker Keith Stroyan
Title The Empirical Motion/Pursuit Law
Room 110 MLH
 
September 17, 2012
3:30 PM
Speaker Mary Therese Padberg
Title TBA
Room 110 MLH
September 24, 2012
3:30 PM
Speaker cancelled
Title
Room 110 MLH
 
   
  
October
 
October 1, 2012   (Invited Speaker)
3:30 PM
Speaker Anne J. Shiu (L.E. Dickson Instructor and NSF Postdoc Department of Mathematics at the University of Chicago)
Title Chemical reaction systems with toric steady states
Abstract:
Chemical reaction networks taken with mass-action kinetics are dynamical systems governed by polynomial differential equations that arise in systems biology. In general, establishing the existence of (multiple) steady states is challenging, as it requires the solution of a large system of polynomials with unknown coefficients. If, however, the steady state ideal of the system is a binomial ideal, then we show that these questions can be answered easily. This talk focuses on systems with this property, and we say such systems have toric steady states. Our main result gives sufficient conditions for a chemical reaction system to admit toric steady states. Furthermore, we analyze the capacity of such a system to exhibit multiple steady states. An important application concerns the biochemical reaction networks networks that describe the multisite phosphorylation of a protein by a kinase/phosphatase pair in a sequential and distributive mechanism. No prior knowledge of chemical reaction network theory or binomial ideals will be assumed. (This is joint work with Carsten Conradi, Mercedes Pérez Millán, and Alicia Dickenstein.)
Room
110 MLH
 
October 3, 2012   (Colloquium Speaker)
3:30 PM
Speaker Suncica Canic (Cullen Distinguished Professor of Mathematics, Director of the Center for the Mathematical Bioscience, University of Houston)
Title Fluid-Structure Interaction in Blood Flow: Modeling, Analysis, and Numerical Simulation
Abstract:
Mathematical modeling, analysis and numerical simulation, combined with imaging and experimental validation, provide powerful tools for studying cardiovascular physiology and pathology. From the mathematics point of view, studying the interaction between blood flow and vascular tissue (fluid-structure interaction, FSI) is particularly complicated due to the multi-physics and multi-scale nature of the problem. Additionally, since the density of cardiovascular tissue is roughly equal to that of blood, classical loosely-coupled FSI numerical methods, which work well in aero-elasticity, are known to be intrinsically unstable in hemodynamics. This is due to the highly nonlinear coupling between the fluid and structure of equal densities. In this talk, the speaker will review the main issues related to the analysis and numerical simulation of fluid-structure interaction (FSI) problems in hemodynamics, and present some most recent results in this area. The results will include the proof of the existence of a solution to a benchmark problem in FSI in blood flow, and the design of a novel loosely-coupled FSI scheme, which is unconditionally stable for the blood flow application.(Results presented in this talk have been obtained together with graduate student M. Bukac, post-doc B. Muha, and Profs. R. Glowinski and A. Quaini.)
Room
213 MLH
 
October 3, 2012   (Third Annual Rockwell Lecture)
7:30 PM
Speaker Suncica Canic (Cullen Distinguished Professor of Mathematics, Director of the Center for the Mathematical Bioscience, University of Houston)
Title What do cardiovascular stents, the World Trade Center, and carbon nano-tubes have in common?
Abstract:
From local to global, and from simple to complex, mathematics can uncover the global properties of complex structures that emerge from the local properties of each component, and from the manner in which local components are composed to form the global topological structure. These emergent global properties of complex net-like structures have recently been used in the design new cardiovascular stents. Stents are used in the treatment of coronary artery disease and in heart valve replacement. Coronary artery disease is a precursor for heart attack, the number one cause of death in the US. The speaker will show how mathematical hyperbolic net theory can be used to understand a wide spectrum of real-life net and network problems, including the application to cardiovascular interventions involving the use of mesh-like stents for the treatment of coronary artery disease.
Room
Lecture Room 1, Van Allen Hall, University of Iowa
October 8, 2012
3:30 PM
Speaker Chenhong Zhu
Title Insight to heart failure using two minimal Ca2+ models
Room 110 MLH
 
October 11, 2012   (Colloquium Speaker)
3:30 PM
Speaker Peter Latham (Gatsby Computational Neuroscience Unit, University College London, UK)
Title Olfaction as probabilistic inference
Abstract:
Inferring what odors are in the air is a hard problem, for at least two reasons: the number of odorant receptor neurons (the first neurons in the olfactory pathway) is smaller than the number of possible odors, and multiple odors can be present at once. Consequently, even if there is a simple mapping from odors to odorant receptor neurons that mapping cannot be uniquely inverted. Presumably, the brain solves this problem by computing the probability that any particular odor is present. We present an inference algorithm that does this, discuss how it maps onto olfactory circuitry, and comment on what we learn about sensory processing in general.
Room
213 MLH
 
October 15, 2012
3:30 PM
Speaker cancelled
Title
Room 110 MLH
 
October 22, 2012
3:30 PM
Speaker Garrett Jones
Title Tangles and Knotted Proteins
Room 110 MLH
 
October 29, 2012
3:30 PM
Speaker cancelled
Title
Room 110 MLH  
  
November
November 5, 2012
3:30 PM
Speaker Annette Honken
Title Network topology as a source of biological information
Room110 MLH
 
November 12, 2012
3:30 PM
Speaker Michael Covello
Title The impact of of sexually abstaining groups on persistence of sexually transmitted infections in populations with ephemeral pair bonds
Room 110 MLH
 
November 19, 2012 (Thanksgiving Week - no seminar)
3:30 PM
Speaker -
Title -
Room-
 
November 26, 2012
3:30 PM
Speaker Gabriela Hamerlinck
Title Can Preadaptations predict the outcomes of parasitoid competition in novel habitats
Room110 MLH  
  
December
December 3, 2012
3:30 PM
Speaker Guanyu Wang
Title Table of 2-string tangles and distances between knots
Room 110 MLH